Method #6 Install Latest Update of the Game After Disabling or Whitelisting the app on your Anti-Virus, check whether the Fallout 4 crash on startup error still occurs. You can check the manual of your particular antivirus to know how to disable or whitelist apps on your Antivirus software. After performing the steps mentioned above, right-click on Steam and then choose Run as administrator. Alternatively, you can check or add Steam to the whitelist of your Antivirus so that conflicts will be avoided. To make sure that your antivirus isn’t doing the same to your game, either disable your antivirus for some time. Our tool will quickly repair common computer errors, protect you from file or data loss, malware, trojans, hardware failure and optimize your PC to boost for maximum performance.